City Guide, St. Louis County, MO
24 Hour and Emergency Vets in St. Louis County, MO
Which St. Louis County hospitals are open all night, which are urgent care only, and what to do before you drive.
By PetVet Directory · October 24, 2026 · 6 min read
In this article7 sections
Your regular vet closed hours ago, and something is wrong. You need to know who is open right now.
If it could be life-threatening, go to a 24/7 emergency hospital in St. Louis County at any hour: VEG ER for Pets in Brentwood, Animal Emergency Clinic in Kirkwood, or Veterinary Specialty Services (VSS) in Manchester. Call on the way.
If it can't wait but isn't life-threatening, UrgentVet in Lemay is an urgent care option during its open hours. This guide covers dogs and cats, plus where to take birds and exotics. Hours were checked October 24, 2026, and can change, so call before you drive.
Where to find a 24 hour emergency vet in St. Louis County
The three ERs above are open 24 hours, 7 days a week. UrgentVet Lemay is in the table so you can see the difference at a glance.
| Clinic | Address | Open 24/7? | Type | Phone |
|---|---|---|---|---|
| VEG ER for Pets, Brentwood | 2101 S Brentwood Blvd, Brentwood, MO 63144 | Yes | Emergency hospital | (314) 970-2545 |
| Animal Emergency Clinic, Kirkwood | 9937 Big Bend Rd, Kirkwood, MO 63122 | Yes | Emergency hospital | (314) 822-7600 |
| Veterinary Specialty Services (VSS), Manchester | 1021 Howard George Dr, Manchester, MO 63021 | Yes | Emergency service in a specialty hospital | (636) 227-6100 (emergency line) |
| UrgentVet Lemay | 2524 Lemay Ferry Rd, St. Louis, MO 63125 | No | Urgent care | (314) 354-5500 |
Take a screenshot so it's on your phone when you need it.
VEG ER for Pets, Brentwood
Open 24 hours a day, 365 days a year, holidays included. No appointment is needed, though calling ahead lets the team get ready, and you can stay with your pet instead of waiting in the lobby. VEG sees dogs, cats, birds, and exotic pets, so start here if your rabbit, bird, or reptile is the one in trouble. Call (314) 970-2545.
Animal Emergency Clinic, Kirkwood
Open 24/7, all year, for dogs and cats, at 9937 Big Bend Rd. Call 314-822-7600. For any other kind of pet, ask on the phone where they can be seen.
Veterinary Specialty Services (VSS), Manchester
VSS is a specialty hospital whose emergency service is always open. Life-threatening cases are handled by its Critical Care team, and pets who stay in the hospital are monitored closely. For an emergency, call the Emergency Line at 636-227-6100. The other number you may see, (636) 227-9400, is the referral line for scheduled specialty visits.
Urgent care vet vs emergency vet: which one tonight?
A 24/7 emergency hospital handles life-threatening problems and pets who need to stay overnight, at any hour. An urgent care clinic fills the gap between your regular vet and the ER for problems that can't wait but aren't life-threatening, and it closes at night. If you aren't sure which side of that line your pet is on, go to the ER.
UrgentVet Lemay (South County)
UrgentVet is open 3 PM to 11 PM Monday through Friday, 10 AM to 8 PM Saturday and Sunday, and 12 PM to 8 PM on holidays. It sees dogs and cats, and you can walk in or save a spot online. It doesn't treat life-threatening emergencies or keep pets overnight. Think an ear infection, a small cut, or an upset stomach in a pet still acting mostly like themselves. Call 314-354-5500.
Your regular vet's same-day slots
Many day clinics will fit in a sick pet the same day during business hours. MetroVet at 920 S Brentwood Blvd, for example, is a primary care practice with same-day appointments and urgent care services, open Monday to Friday, 8 AM to 6 PM. It is not an ER. If your pet gets sick in the morning, call your own vet first.
What counts as a pet emergency?
Go to a 24/7 hospital now for trouble breathing, collapse, straining to pee with little or nothing coming out, or repeated tries to throw up with nothing coming up and a swollen belly. Possible poisoning, a serious injury, bleeding that won't stop, and seizures also count. For the full list and what each sign means, read 7 signs your pet needs an emergency vet tonight.
Not sure? Call first
Any of the three ERs will tell you on the phone whether to come in, and calling lets them know you're on the way. If your pet ate something that might be poisonous, call an ER or an animal poison control line right away, even if your pet seems fine.
How much does a 24 hour or emergency vet visit cost?
An ER visit usually costs more than a regular vet or urgent care visit. You're paying for a fully staffed hospital at any hour, and the pets who come in are often sicker. The final bill depends mostly on what your pet needs after the exam:
- The emergency exam fee
- Tests like bloodwork, X-rays, or ultrasound
- Treatment such as IV fluids, medicine, or oxygen
- Surgery, if it's needed
- Staying overnight in the hospital, which is often the biggest part
Ask for a written estimate before treatment starts, and ask what has to happen tonight and what can wait for your regular vet. For questions to ask a clinic before you need one, see how to choose a veterinarian.
Is a 24 hour vet more expensive?
Generally, yes, compared with a day clinic. Urgent care is the in-between choice when it's open and the problem isn't life-threatening.
What to do if you can't afford an emergency vet
Don't skip care. Call the ER, tell them your budget up front, and ask for an estimate with treatment options at different price points. Ask:
- Whether payment is due at the time of the visit
- Whether they accept veterinary financing, a medical credit card, or a payment plan
- Whether your pet insurance covers ER visits, and what paperwork a claim needs
- Whether it's safe to stabilize your pet tonight and follow up with your regular vet
- What their policy is on unpaid bills, before treatment starts
Before you need it: save these numbers
- Your regular vet's after-hours instructions (many have a recorded message that says where to go)
- The 24/7 hospital closest to home, and the one closest to work
- UrgentVet Lemay's hours, if you live in South County
- Your pet's records and medicine list, saved on your phone
Don't have a regular vet yet? Find a regular vet in St. Louis or browse vets in Creve Coeur.
Common questions
Is there a 24 hour emergency vet in St. Louis County?
Yes, three: VEG ER for Pets in Brentwood, Animal Emergency Clinic in Kirkwood, and VSS in Manchester, all listed in the table above with addresses and phone numbers.
What's the difference between an urgent care vet and an emergency vet?
Urgent care closes at night and can't keep your pet overnight, so anything life-threatening belongs at an ER. See which one tonight.
What counts as an emergency for a vet visit?
If your pet can't breathe well, collapses, or can't pee, go now. 7 signs your pet needs an emergency vet tonight covers the rest.
Is a 24 hour vet more expensive than a regular vet?
Usually, because ER cases tend to need more tests and care. Overnight stays are often the biggest line on the bill.
How much does an emergency vet visit cost in St. Louis?
There's no set price, since the bill grows with each test and treatment. A written estimate before anything starts is your best guide.
What can I do if I can't afford the emergency vet?
Go anyway and say your budget out loud at the front desk. Our list of questions to ask helps you find a workable plan.
Is there a 24 hour emergency vet near Creve Coeur?
Not in Creve Coeur itself; VEG in Brentwood, VSS in Manchester, and Animal Emergency Clinic in Kirkwood are the closest. VCA Bal-Coeur Animal Hospital in Creve Coeur is a daytime hospital, not a 24 hour ER.
Do I need an appointment at an emergency vet?
No, ERs take walk-ins and see the sickest pets first, so waits change through the night. UrgentVet lets you save a spot online.
Clinics mentioned in this guide
Find a vet nearby
Compare reviews, hours, and services at clinics in the places this guide covers.
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